This volume includes essays that deploy interdisciplinary approaches to the analysis of the mutual relationship between pandemics and the built environment. The chapters cover case studies from all five continents. Each chapter will focus on the story of a pandemic in a particular city or region. The chapters will be brief (1700–2000 words) and will be developed based on a strict structure provided by the book editors. Each chapter will include historical context (500 words), case study (700 words), and conclusion (300 words). Each chapter will include 3–4 historical images that depict historical epidemics and pandemics. The book will be opened and concluded by two well-known scholars from public health and medical anthropology. These two chapters will address pandemics and epidemics in the last fifty years as well as the COVID-19 crisis and how history helps us have a better understanding of the post-COVID era.